Analysis of pregnancy outcomes in elderly patients with multiple pregnancies undergoing early pregnancy reduction during assisted reproduction
Objective To investigate the pregnancy outcomes of multiple pregnancies after assisted reproduction in elderly infertile patients,and analyze its necessity and safety.Methods A retrospective analysis of 191 cases of infertility patients≥35 years old who underwent assisted reproductive technology(ART)to obtain the clinical data of multiple pregnancy reduction,110 cases of which were in the group of keeping single birth after reduction to single birth(including 2 cases of four birth reduction to single birth,21 cases of three birth reduction to single birth,87 cases of twin birth reduction to single birth).81 cases were in the reduced twins group(including 1 case of four reduced twins and 80 cases of three reduced twins).In addition,454 cases of ART singleton pregnancies aged ≥35 years in the same period were randomly selected as the unreduced singleton group,and the abortion rate,premature delivery rate,cesarean section rate,gestational week of delivery,newborn birth weight,low birth weight infants and other conditions of the three groups were compared.Results The early abortion rate,premature birth rate,cesarean section rate and low birth weight rate in single group were lower than those in twin group(P＜0.05).The preterm birth rate,cesarean section rate and incidence of low birth weight infants in the unreduced single group were lower than those in the reduced single group(P＜0.05).Conclusion For elderly infertile patients with multiple pregnancies through assisted reproduction,fetal reduction in early pregnancy can effectively reduce the rate of premature delivery and cesarean section,prolong the gestational week of delivery,and reduce the risk of low birth weight infants.
NETL
NSTL
万方数据
