首页|宫腔镜手术联合地屈孕酮治疗子宫内膜息肉效果分析

宫腔镜手术联合地屈孕酮治疗子宫内膜息肉效果分析

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目的 探讨子宫内膜息肉患者行宫腔镜手术治疗后联合地屈孕酮治疗的效果。方法 选取50例子宫内膜息肉患者为研究对象,根据随机数字表法分为对照组和研究组,每组25例。对照组实施宫腔镜手术治疗,研究组在对照组基础上给予地屈孕酮治疗,比较两组治疗前后子宫内膜厚度、月经失血评估表(PBAC)评分及异常子宫出血情况。结果 治疗前,两组子宫内膜厚度、PBAC评分比较差异均无统计学意义(P>0。05);治疗后,研究组子宫内膜厚度小于对照组、PBAC评分低于对照组(P<0。05);术后3个月,两组异常子宫出血发生率比较差异无统计学意义(P>0。05);术后5个月,研究组异常子宫出血发生率低于对照组(P<0。05)。结论 子宫内膜息肉采用地屈孕酮联合宫腔镜手术治疗效果较好,可有效调节患者术后雌孕激素受体表达,改善月经异常,并缩减子宫内膜厚度,减少异常子宫出血,值得临床推广与应用。
Effect analysis of hysteroscopic surgery combined with dydrogesterone in the treatment of endometrial polyps
Objective To investigate the effect of combined desdrogesterone therapy on patients with endometrial polyps after hysteroscopic surgery.Methods A total of 50 patients with endometrial polyps were selected as research objects and divided into control group and study group according to random number table method,with 25 cases in each group.The control group received hysteroscopic surgery,and the study group received dydrogesterone treatment on the basis of the control group.The endometrial thickness,menstrual blood loss assessment scale(PBAC)score and abnormal uterine bleeding before and after treatment were compared between the two groups.Results Before treatment,there were no significant differences in endometrial thickness and PBAC score between the two groups(P>0.05).After treatment,the endometrial thickness of the study group was less than that of the control group,and the PBAC score was lower than that of the control group(P<0.05).Three months after surgery,there was no significant difference in the incidence of abnormal uterine bleeding between the two groups(P>0.05).5 months after operation,the incidence of abnormal uterine bleeding in the study group was lower than that in the control group(P<0.05).Conclusion Desdrogesterone combined with hysteroscopic surgery is effective in the treatment of endometrial polyps,which can effectively regulate the expression of estrogen receptor,improve abnormal menstruation,reduce endometrial thickness,and reduce abnormal uterine bleeding,which is worthy of clinical promotion and application.

Endometrial polypHysteroscopic surgeryDydrogestoneTherapeutic effect

张小惠、杨旭、刘妍、孙亚新

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江苏省无锡市惠山区中医医院 妇科,江苏 无锡 214100

子宫内膜息肉 宫腔镜手术 地屈孕酮 治疗效果

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(4)
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