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胰岛素治疗妊娠期糖尿病的效果分析

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目的 探讨妊娠期糖尿病(GDM)孕妇采用胰岛素治疗的效果。方法 选取60例待产GDM孕妇为研究对象,按照抽签奇偶数分为对照组和研究组,每组30例。对照组采用常规疗法,研究组采用胰岛素泵[即持续皮下胰岛素输注(CSII)]疗法,比较两组不良反应、不良妊娠结局发生率、血糖指标。结果 治疗后,两组不良反应总发生率比较差异无统计学意义(P>0。05);研究组不良妊娠结局发生率低于对照组(P<0。05);治疗前,两组空腹血糖(FBG)、餐后2 h血糖(2hPBG)水平比较差异均无统计学意义(P>0。05);治疗后,两组FBG、2hPBG水平均低于治疗前,且研究组低于对照组(P<0。05)。结论 GDM孕妇采用CSII治疗效果较好,可调节孕妇血糖水平,改善其不良妊娠结局,且安全性较好,值得临床推广与应用。
Effect of insulin on gestational diabetes mellitus
Objective To investigate the effect of insulin therapy in pregnant women with gestational diabetes mellitus(GDM).Methods A total of 60 pregnant women with GDM waiting for delivery were selected as the study objects and divided into control group and study group according to the odd and even number of lots,with 30 cases in each group.The control group received conventional therapy,and the study group received insulin pump(continuous subcutaneous insulin infusion,CSII)therapy.Adverse reactions,incidence of adverse pregnancy outcomes,and blood glucose indexes were compared between the two groups.Results After treatment,there was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).The incidence of adverse pregnancy outcome in the study group was lower than that in the control group(P<0.05).Before treatment,there were no significant differences in Fasting blood glucose(FBG)and 2 h postprandial blood glucose(2hPBG)levels between the two groups(P>0.05).After treatment,the levels of FBG and 2hPBG in both groups were lower than before treatment,and the study group was lower than the control group(P<0.05).Conclusion CSII is effective in the treatment of pregnant women with GDM,which can regulate the level of blood sugar in pregnant women,improve the adverse pregnancy outcome,and is safe,which is worthy of clinical promotion and application.

Gestational diabetes mellitusInsulin pumpContinuous subcutaneous insulin infusionTherapeutic effect

王彤辉、丁文、胡迟秀

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青岛市胶州中心医院 药剂科,山东 青岛 266300

妊娠期糖尿病 胰岛素泵 持续皮下胰岛素输注 治疗效果

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(4)
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