Clinical study on the treatment of psychogenic luteal insufficiency infertility with the method of tonifying the kidney and regulating the menstrual cycle
Objective To analyze the therapeutic effect of tonifying the kidney and regulating the menstrual cycle method on psychogenic luteal insufficiency infertility.Methods 40 patients with psychogenic luteal insufficiency infertility in our hospital were selected as the research subjects,and a cohort study was used to divide them into two groups,with 20 cases in each group.Patients in the traditional Chinese medicine group were treated with sequential therapy of tonifying the kidney and regulating the menstrual cycle,while patients in the western medicine group were treated with letrozole to promote ovulation.Observe the changes in life event scale scores,clinical pregnancy rates,basal luteinizing hormone(LH),mid luteal progesterone(P)and estradiol(E2),kissing hormone,adrenocorticotropic hormone,cortisol levels,and traditional Chinese medicine syndrome scores before and after treatment in two groups.Results After treatment,the levels of LH and mid luteal E2 and P,as well as plasma kissing hormone levels,were significantly increased in both groups at baseline,and the traditional Chinese medicine group was higher than the western medicine group(P＜0.05).The levels of adrenocorticotropic hormone,cortisol,traditional Chinese medicine syndrome scores,and life event scale scores were all reduced in both groups,and the traditional Chinese medicine group was lower than the western medicine group(P＜0.05).The clinical pregnancy rate in the traditional Chinese medicine group was 40％,which was higher than 20％in the Western medicine group(P＜0.05).The total effective rate of the traditional Chinese medicine group was significantly higher than that of the western medicine group(P＜0.05).During the treatment period,no serious adverse reactions were observed in both groups of patients.Conclusion The treatment of psychogenic luteal insufficiency infertility using the method of tonifying the kidney and regulating the menstrual cycle has a definite therapeutic effect,can significantly improve the clinical symptoms of patients,and can effectively increase the pregnancy rate of patients.The medication is safe.
Tonifying the kidney and regulating the menstrual cycleLuteal insufficiencyInfertilityClinical research
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NSTL
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