个性化医学营养疗法联合二甲双胍治疗妊娠期糖尿病患者的疗效探讨
Clinical efficacy of personalized medicine nutrition therapy combined with metformin in the treatment of gestational diabetes mellitus
郝菲 1杨莹 1刘敏2
作者信息
- 1. 山东省青岛市胶州中心医院 内分泌科,山东青岛 266300
- 2. 山东省青岛市胶州中心医院心内科,山东青岛 266300
- 折叠
摘要
目的 探究个性化医学营养疗法联合二甲双胍治疗妊娠期糖尿病患者的临床疗效.方法 选取96例妊娠期糖尿病患者,利用随机抽签法分组,每组48例.对照组予以个性化医学营养疗法,观察组在对照组基础上联合二甲双胍.比较两组血糖水平和不良妊娠结局发生率.结果 干预后观察组空腹血糖、餐后2 h血糖、糖化血红蛋白水平均明显低于对照组(P＜0.05).观察组新生儿低血糖率4.17％、早产率6.25％、剖宫产率18.75％均明显低于对照组的16.67％、20.83％、37.50％(P＜0.05).结论 妊娠期糖尿病患者予以个性化医学营养疗法联合二甲双胍治疗可更有效控制血糖水平,降低不良妊娠结局发生率,具有临床推广价值.
Abstract
Objective To explore the clinical efficacy of personalized medicine nutrition therapy combined with metformin in the treatment of gestational diabetes mellitus.Methods 96 patients with gestational diabetes mellitus were selected and divided into 48 cases in each group by random drawing method.The control group was given personalized medicine nutrition therapy,and the observation group was combined with metformin on the basis of the control group.Blood glucose levels and incidence of adverse pregnancy outcomes were compared between the two groups.Results After intervention,the levels of fasting blood glucose,2 h postprandial blood glucose and HBA1c in the observation group were significantly lower than those in the control group(P＜0.05).The neonatal hypoglycemia rate of 4.17％,premature delivery rate of 6.25％and cesarean section rate of 18.75％in the observation group were significantly lower than those in the control group16.67％,20.83％and 37.50％(P＜0.05).Conclusion Personalized medicine nutrition therapy combined with metformin can more effectively control blood glucose level and reduce the incidence of adverse pregnancy outcomes in patients with gestational diabetes,which has clinical promotion value.
关键词
妊娠期糖尿病/个性化医学营养疗法/二甲双胍Key words
Gestational diabetes mellitus/Personalized medicine nutrition therapy/Metformin引用本文复制引用
出版年
2024
NETL
NSTL
万方数据