The relationship between serum 25 hydroxyvitamin D levels in early pregnancy of pregnant women and perinatal depression and bone density
Objective To explore the relationship between serum 25 hydroxyvitamin D levels in early pregnancy and perinatal depression and bone density.Methods 120 early single pregnancy pregnant women registered in our hospital were selected as the research subjects.Through data collection,venous blood was collected from pregnant women,and serum 25 hydroxyvitamin D levels were detected using radioimmunoassay.According to serum 25 hydroxyvitamin D levels,pregnant women were divided into normal vitamin D group,vitamin D deficiency group,vitamin D deficiency group,and vitamin D severe deficiency group,30 cases each.The depression level and bone density level of each group were compared.Results The serum 25 hydroxyvitamin D levels and T-score index of the normal vitamin D group were higher than those of the vitamin D deficiency group,vitamin D deficiency group,and severe vitamin D deficiency group.The Edinburgh Postpartum Depression Scale score was lower than that of the vitamin D deficiency group,vitamin D deficiency group,and severe vitamin D deficiency group,and the difference was statistically significant(P＜0.05);Pearson correlation analysis showed that serum 25 hydroxyvitamin D levels in early pregnancy women were significantly positively correlated with depression and bone density(r=0.273,r=0.726,P＜0.05).Conclusion The serum 25 hydroxyvitamin D levels in early pregnancy have a direct impact on perinatal depression and bone density.Therefore,paying attention to changes in serum 25 hydroxyvitamin D levels in early pregnancy may reduce the occurrence of perinatal depression and osteoporosis.
Early pregnancySerum 25 hydroxyvitamin DPerinatal periodDepressionBone density
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