多囊卵巢综合征真实世界病例分析
Real world case analysis of polycystic ovary syndrome
枚芳芳 1冯丽群 1王小红 1王莉云1
作者信息
- 1. 广州市花都区妇幼保健院(胡忠医院)生殖医学科,广东广州 510800
- 折叠
摘要
目的 探讨多囊卵巢综合征(PCOS)的人群特征与妊娠结局,为临床提供参考.方法 通过病历注册研究方法收集PCOS患者资料进行数据分析.结果 完成病历注册391例;截至末次随访,98例成功妊娠,293例未妊娠,妊娠率为25.1％.98例成功妊娠的病例,15例进行人工授精未孕,后行试管婴儿,54例直接行试管婴儿,20例指导同房,9例人工授精.293例未妊娠的病例,其中215例为指导同房,35例为试管婴儿,36例采用人工授精,7例采用人工授精未孕,行试管婴儿.结论 对实现妊娠需要医疗辅助的PCOS人群集中在病程＞3年.月经周期延长、合并超重、肥胖是PCOS的临床特点.痛经发作次数、月经持续时间延长、月经初潮过早或过晚可能不是本病的特点.指导同房在促使PCOS患者妊娠应用价值有限.试管婴儿、人工授精在PCOS的辅助生殖中具有较好的应用价值.
Abstract
Objective To investigate polycystic ovarian syndrome population characteristics and pregnancy outcomes for provide clinical reference.Methods The data of PCOS cases were collected and analyzed by case registration.Results 391 cases were registered;Up to the last follow-up,98 cases of successful pregnancy and 293 cases of non-pregnancy,the pregnancy rate was 25.1％.98 cases of successful pregnancy,15 cases of artificial insemination did not get pregnant,later IVF,54 cases of direct IVF,20 cases of guided sex,9 cases of artificial insemination.293 cases were not pregnant,of which 215 were guided sex,35 were IVF,36 were artificial insemination and 7 were not pregnant by IVF.Conclusion The PCOS population requiring medical assistance to achieve pregnancy events is concentrated in the disease course greater than 3 years.Prolonged menstrual cycle,combined with overweight and obesity are the clinical characteristics of PCOS.The frequency of menstrual cramps,prolonged menstrual duration,and early or late menarche may not be characteristic of the disease.Cohabitation is of limited value in promoting pregnancy with PCOS.Ivf and artificial insemination have good application value in assisted reproduction of PCOS.
关键词
多囊卵巢综合征/真实世界研究/生殖Key words
Polycystic ovary syndrome/Real world research/Reproduction引用本文复制引用
基金项目
2022年花都区医疗卫生一般科研专项项目(22-HDWS-103)
出版年
2024
NETL
NSTL
万方数据