Clinical study of low molecular weight heparin sodium combined with progesterone in treatment of threatened abortion in early pregnancy
Objective To study the clinical value of low molecular weight heparin sodium combined with progesterone in the treatment of threatened abortion in early pregnancy.Methods 40 patients with threatened abortion in early pregnancy were selected and divided into two groups according to random number table method,with 20 cases in each group.The control group was treated with progesterone alone,and the study group was treated with low molecular weight heparin sodium on the basis of the control group.The clinical effect and safety of the two groups were compared.Results The total effective rate of the study group was 100％,which was higher than that of the control group(70.00％),the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in the levels of progesterone(P)and human chorionic gonadotropin(β-HCG)between the two groups(P＞0.05).After treatment,the levels of P and β-HCG in the study group were higher than those in the control group,and the difference was statistically significant(P＜0.05).The incidence of adverse reactions in the study group was 5.00％,which was not statistically significant compared with 10.00％in the control group(P＞0.05).Conclusion Low molecular weight heparin sodium combined with progesterone therapy can improve the efficacy of medication for threatened abortion in early pregnancy,more effectively regulate the level of reproductive hormones in patients,and ensure the safety of medication,which is worthy of clinical promotion.
Threatened miscarriage in early pregnancyLow molecular weight heparin sodiumProgesterone
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