Clinical observation of umbilical needle combined with letrozole in the treatment of kidney deficiency phlegm-dampness PCOS with infertility
Objective To explore the clinical effect of umbilical needle combined with letrozole in the treatment of kidney deficiency phlegm-dampness polycystic ovary syndrome(PCOS)with infertility.Methods 80 patients with kidney deficiency and phlegm-dampness PCOS with infertility were selected and divided into umbilical acupuncture combined with letrozole group(treatment group)and letrozole group(control group)according to random number table method,with 40 cases in each group.The clinical efficacy,endometrial thickness during ovulation,luteinizing hormone(LH),follicle stimulating hormone(FSH),testosterone(T),insulin resistance index(HOMA-IR),fasting insulin(FINS),fasting blood glucose(FBG)and pregnancy rate were compared between the two groups.Results The total effective rate of 90.00％in the treatment group was significantly higher than 70.00％in the control group,and the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in HOMA-IR,FINS and FBG levels between the two groups(P＞0.05).After treatment,the levels of HOMA-IR,FINS and FBG in both groups showed a decreasing trend,and the treatment group was significantly lower than the control group,the difference was statistically significant(P＜0.05).There was no significant difference in FSH,LH and T levels between the two groups before treatment(P＞0.05).After treatment,the levels of FSH,LH and T in both groups showed a downward trend,and there was no statistical significance in the level of FSH between the two groups(P＞0.05).The levels of LH and T in the treatment group were significantly lower than those in the control group,with statistical significance(P＜0.05).There was no significant difference in endometrial thickness between the two groups before treatment(P＞0.05).After treatment,endometrial thickness of both groups showed an increasing trend,and the treatment group was significantly thicker than the control group,the difference was statistically significant(P＜0.05).The clinical pregnancy rate of the treatment group was significantly higher than that of the control group,and the spontaneous abortion rate was lower than that of the control group,the difference was statistically significant(P＜0.05).Conclusion Umbilical acupuncture combined with letrozole can significantly improve the pregnancy rate of PCOS infertility with kidney deficiency and phlegm-dampness by adjusting hormone levels and increasing endometrial thickness.
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