Effects of hyperbaric oxygen combined with low molecular weight heparin on vascular endothelial function and maternal and infant outcomes in hypertensive diseases during pregnancy
Objective To study the effects of hyperbaric oxygen combined with low molecular weight heparin on vascular endothelial function and maternal and infant outcomes in hypertensive diseases during pregnancy.Methods 100 patients with hypertensive diseases in pregnancy were selected and divided into 50 cases in each group according to the odd and even number of visits.The control group was treated with low molecular weight heparin,and the experimental group was treated with hyperbaric oxygen combined with low molecular weight heparin.The therapeutic effect of the two groups was compared.Results After treatment,the levels of systolic and diastolic blood pressure in experimental groups were lower than those in control group(P＜0.05).After treatment,the vascular endothelial function of experimental group was better than that of control group(P＜0.05).The incidence of adverse outcomes in the experimental group was 8.00％lower than that in the control group(26.00％)(P＜0.05).Conclusion In the treatment of hypertensive diseases during pregnancy,hyperbaric oxygen combined with low molecular weight heparin can not only reduce the blood pressure level of patients,but also improve the vascular endothelial function and reduce the adverse outcome of mothers and infants,which is worthy of clinical promotion.
Hyperbaric oxygenLow molecular weight heparinHypertensive diseases during pregnancyVascular endothelial functionMaternal and infant effects
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