The clinical effect of recombinant interferon α-2b combined with CO2 laser gasification in the treatment of cervical low-grade intraepithelial lesions with HR-HPV infection and its impact on HPV negative conversion rate
Objective To analyze the clinical effect of recombinant interferon α-2b combined with CO2 laser gasification in the treatment of cervical low-grade intraepithelial lesions with high-risk human papillomavirus(HR-HPV)infection.Methods 80 patients with cervical low-grade intraepithelial lesions with HR-HPV infection were selected and were divided into a control group and a study group by random number table method,with 40 cases in each group.The control group was treated with recombinant interferon α-2b,and the study group was treated with recombinant interferon α-2b combined with CO2 laser gasification.The therapeutic effects of the two groups were compared.Results The total effective rate of the study group was 90.00％,which was higher than 72.50％of the control group(P＜0.05).The HPV negative conversion rate in the study group were higher than those in the control group at 3 and 6 months after treatment(P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Recombinant interferon α-2b combined with CO2 laser gasification in the treatment of cervical low-grade intraepithelial lesions with HR-HPV infection can improve the curative effect and HPV negative conversion rate.
Recombinant interferon α-2bCO2 laser gasificationCervical low-grade intraepithelial lesionsHigh-risk human papillomavirus
NETL
NSTL
万方数据
