Analysis of the diagnostic value of combined detection of tumor markers in gynecological tumors
Objective To explore the effectiveness of using tumor marker combined detection in the diagnosis of gynecological tumors.Methods 64 gynecological tumor patients admitted to our hospital were selected as the research subjects.According to the pathological diagnosis results of postoperative patients,they were divided into benign tumor group(n=32)and malignant tumor group(n=32).Then,gynecological health examination personnel in the same period of the hospital were selected as the health reference group(n=32),and all three groups received CEA,CA125,and CA199 testing.The diagnostic efficacy of each group's indicator level and combined indicator testing was analyzed.Results The levels of CEA,CA125,and CA199 in the malignant tumor group were(9.84±1.48)ng/ml,(198.16±17.38)IU/ml,and(85.47±7.49)IU/ml,respectively,higher than those in the benign tumor group and the healthy control group.Moreover,the levels of CEA,CA125,and CA199 in the benign tumor group were higher than those in the healthy control group(P＜0.05).The diagnostic sensitivity of the combined test was 78.13％(25/32),significantly higher than that of CEA,CA125,and CA199 alone.The diagnostic specificity of the combined test was 53.13％(17/32),significantly higher than that of CEA and CA199 alone(P＜0.05).There was no difference in the specificity between the combined test and CA125 alone(P＞0.05)).Conclusion Tumor markers in patients with gynecological tumors have increased to varying degrees,with higher levels in patients with malignant tumors.Combined indicator testing can significantly improve the positive detection rate of gynecological tumors and has high diagnostic efficacy,which is worthy of clinical promotion and application.
Tumor markersJoint testingGynecological tumorsDiagnostic value
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