Role of TCT combined with high-risk HPV detection in cervical cancer screening
Objective To investigate the role of thinprep cytologic test(TCT)+with high-risk human papillomavirus(HPV)in cervical cancer screening.Methods 120 women who underwent cervical cancer screening in the hospital were selected as the study objects,and all of them underwent TCT combined with high-risk HPV detection.The screening results were statistically analyzed,and the detection rate and diagnostic efficiency were analyzed.Results The results of pathological examination were the gold standard.Among 120 cases,79 cases were high risk HPV positive,the positive coincidence rate with pathological examination was 92.41％and the negative coincidence rate was 68.29％;74 cases were TCT positive,the positive coincidence rate was 89.19％and the negative coincidence rate was 76.09％;the detection rates of cervical intraepithelial neoplasia(CIN)ⅠCIN Ⅱ,CIN Ⅲ and squamous cell carcinoma by combined detection were higher than those by single detections(P＜0.05).The sensitivity,specificity and accuracy of TCT were 89.61％,88.37％and 89.17％,respectively;and were 93.51％,83.72％and 90.00％of high-risk HPV detection;and were 94.81％,93.02％and 94.17％of combined detection;the sensitivity,specificity and accuracy of combined detection were slightly higher than those of single detections,but the differences were not statistically significant(P＞0.05).Conclusion The application value of TCT combined with high-risk HPV detection in cervical cancer screening is high,which can improve the detection rate of cervical cancer and precancerous lesions,and reduce the incidence of misdiagnosis and missed diagnosis.
Cervical cancerThinprep cytologic testHigh-risk human papillomavirus test
NETL
NSTL
万方数据
