Analysis of the role of TCT combined with HPV detection in screening early cervical cancer in women
Objective To analyze the role of TCT combined with HPV detection in early cervical cancer screening in women aged 35-65.Methods A total of 5000 women screened for early cervical cancer in our hospital were selected as the research subjects.All examined women underwent liquid based thin-layer cell testing(TCT)and HPV(high-risk human papillomavirus DNA test),and the biopsy pathological results were used as the"gold standard"to calculate the screening effects of different testing methods.Results The detection rate of TCT combined with HPV detection in early cervical cancer was significantly higher than that of the two methods used alone,and the difference was statistically significant(P＜0.05).The positive detection rate of TCT in SCC,HSIL,and LSIL was significantly lower than that in normal and inflamed women with HPV,and the difference was statistically significant(P＜0.05).Compared with the"gold standard"test results,the detection rate of CIN grade Ⅲ and above lesions in TCT combined with HPV testing is very high,and the screening effect is significant,with statistical significance(P＜0.05).Conclusion The application of TCT combined with HPV detection in the screening process of early cervical cancer in women of childbearing age is highly sensitive to the detection rate of diseased tissues,which can effectively improve the screening detection rate and reduce missed diagnosis and misdiagnosis.
Liquid based cytology examinationHigh risk human papillomavirus DNA testingEarly cervical cancerWomen aged 35-65Screening effectiveness
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