The effect of tonifying the kidney,strengthening the spleen,and removing blood stasis combined with letrozole in the treatment of ovulation disorders in phlegm dampness type polycystic ovary syndrome
Objective To explore the effect of tonifying the kidney,strengthening the spleen,and removing blood stasis combined with letrozole in the treatment of ovulation disorders in phlegm dampness type polycystic ovary syndrome(PCOS).Methods 80 patients with phlegm dampness type PCOS ovulation disorders were selected as the research subjects,and were randomly divided into an experimental group(n=40)and a control group(n=40)according to the principle of a random number table.The control group was treated with letrozole,while the experimental group was treated with kidney tonifying,spleen strengthening,and blood stasis removing methods on the basis of the control group.The treatment effects,reproductive hormones,follicle development,and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the experimental group was 95.00％,significantly higher than the control group's 77.50％(P＜0.05);After treatment,the levels of anti Mullerian hormone and inhibin B in the experimental group were lower than those in the control group,the number of follicles was less than that in the control group,and the diameter of follicles was larger than that in the control group(P＜0.05);There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion For the ovulation disorders of phlegm dampness type PCOS patients,the combination of tonifying the kidney,strengthening the spleen,and removing blood stasis method with letrozole has a significant effect,effectively regulating serum reproductive hormone levels,promoting follicular development,and not increasing adverse reactions.It is worth promoting.
Polycystic ovary syndromeOvulation disordersPhlegm dampness typeLetrozoleThe method of tonifying the kidney,strengthening the spleen,and removing blood stasisReproductive hormonesFollicular development
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