Correlation analysis of triglyceride-glucose index and insulin resistance in patients with polycystic ovary syndrome
Objective To investigate the correlation between triglyceride-glucose(TyG)index and insulin resistance(IR)in patients with polycystic ovary syndrome(PCOS).Methods 73 patients with PCOS were selected as the study object,and were divided into 24 patients in the IR group(HOMA-IR≥2.69)and 49 patients in the non-IR group(HOMA-IR＜2.69)according to the results of homeostasis model assessment of insulin resistance(HOMA-IR＜2.69).Fasting blood glucose(FPG),insulin(INS),triglyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C)levels,height and weight were measured.Body Mass index(BMI).The glucolipid metabolism indexes of the two groups were compared,and the diagnostic efficacy of TyG and other indexes in predicting IR was analyzed.Results BMI,FPG,INS,HOMA-IR,TC,TG,LDL-C,TyG,LDL-C/HDL-C,TG/HDL-C and dyslipidemia rates in IR group were significantly higher than those in non-IR group,with statistical significance(P＜0.05).The area(AUC)under receiver operating characteristic curve(ROC)predicted by TyG for IR was 0.825,the cutoff value was 8.625,and the sensitivity and specificity were 70.8％and 81.6％,respectively.Conclusion TyG is a good biomarker for predicting PCOS combined with IR.
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