Comparison of the therapeutic effects of progesterone and Mirena after endometrial polypectomy under hysteroscopy
Objective To explore the preventive methods and clinical effects of hysteroscopy for postoperative recurrence of endometrial polyps(EP).Methods 150 patients with EP in our hospital were selected as the research subjects,and were divided into three groups based on different postoperative preventive measures,with 50 cases in each group.The control group did not take any preventive measures.The progesterone group received oral progesterone after surgery,while the Mirena group received mannitol ring treatment after surgery.The postoperative polyp recurrence rate,endometrial thickness,and incidence of adverse reactions were compared among the three groups of patients.Results At 6 months after treatment,the recurrence rate of polyps in the control group was 6.0％,while there were no recurrence cases in the other two groups(P＜0.05).At 12 months after treatment,the recurrence rate of polyps in the control group was 10.0％,in the progesterone group it was 6.0％,and in the Mirena group there were no recurrence cases;And the total recurrence rate of the control group was higher than that of the progesterone group and higher than that of the mannitol group(P＜0.05).At 3,6,and 12 months of treatment,the endometrial thickness of patients showed a gradually decreasing trend,and the endometrial thickness in the Mirena group was less than that in the progesterone group and less than that in the control group(P＜0.05).The total incidence of adverse reactions in the control group,progesterone group,and Mirena group was 14.0％,12.0％,and 4.0％,respectively,with statistically significant differences between the groups(P＜0.05).Conclusion After hysteroscopic endometrial resection,the addition of progesterone or Mirena ring can improve the thickness of the patient's endometrium,which is beneficial for preventing and reducing polyp recurrence.However,compared to the progesterone group,the incidence of adverse reactions and recurrence after installing mannitol ring is lower,and the effect is better.
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