Study on the correlation between blood glucose control level and fetal macrogenesis in the middle and late pregnancy of gestational diabetes mellitus
Objective To explore the relationship between the level of blood glucose control in the middle and late pregnancy and macrosomia in pregnant women with diabetes mellitus(GDM).Methods We retrospectively collected 150 pregnant women with gestational diabetes(GDM group)and 150 non GDM pregnant women(non GDM group)from 2021 to 2024 in the medical record system of our hospital,collected blood glucose levels in the middle and late pregnancy,and analyzed the relationship between neonatal weight and blood glucose control level.Results The fasting blood glucose(FBG)and glycated hemoglobin(HbA1c)levels in the GDM group during mid to late pregnancy were significantly higher than those in the non GDM group.The birth weight of newborns(3.55±0.42)kg and the incidence of macrosomia(12.0%)were higher than those in the non GDM group(3.11±0.12)kg and 4.67%,respectively(P＜0.05).The levels of FBG and HbA1c in pregnant women with macrosomia during the middle and late stages of pregnancy were significantly higher than those in the non macrosomia group(P＜0.05).Spearman correlation analysis showed that serum FBG and HbA1c were positively correlated with the occurrence of macrosomia(P＜0.05).Conclusion Both FBG and HbA1c in the second and third trimester of gestational diabetes mellitus are related to the birth of macrosomia.Blood glucose monitoring and management should be strengthened during pregnancy to reduce the incidence of macrosomia.
万方数据
维普
