Correlation between ovarian blood flow parameters and hormone levels by vaginal doppler ultrasound
Objective To investigate the correlation between ovarian blood flow parameters and hormone levels in patients with obese and nonobese polycystic ovary syndrome(PCOS).Methods 96 PCOS patients were selected and divided into obese group(42 cases,≥25 kg/m2)and non-obese group(54 cases,<25 kg/m2)according to body mass index(BMI).Both groups underwent vaginal Doppler ultrasonography to determine ovarian blood flow parameters and hormone levels,and analyze the relationship between ovarian blood flow parameters and hormone levels.Results The pulsatility index(PI)and resistance index(RI)of the obese group were higher than those of the non-obese group(P<0.05).There was no significant difference in systolic maximum blood flow velocity(PSV)and diastolic maximum blood flow velocity(EDV)between the two groups(P>0.05).The levels of luteinizing hormone(LH)and follicle stimulating hormone(FSH)in obese group were lower than those in non-obese group(P<0.05).There was no significant difference in the levels of progesterone(P),testosterone(T),prolactin(PRL)and estradiol(E2)between the two groups(P>0.05).The Pearson correlation analysis showed that PI and RI were negatively correlated with LH and FSH levels in PCOS patients(P<0.05).Conclusion The ovarian blood flow parameters were different in obese and non-obese PCOS patients,which was mainly related to LH and FSH hormone levels.