Evaluation of the relationship between myocardial damage and left ventricular diastolic function in patients with acute myocardial infarction using cardiovascular MR T2WI sequences
Objective To explore the evaluation of the relationship between myocardial damage and left ventricular diastolic function in patients with acute myocardial infarction(AMI)by using cardiovascular MR T2WI sequences.Methods A total of 155 AMI patients were selected.All patients were divided into two groups based on whether left ventricular diastolic dysfunction occurred,including diastolic dys-function group and diastolic normal group.Clinical data of all patients,myocardial injury and cardiac function indicators at admis-sion,black blood T2 short time inversion recovery(T2-STIR)sequence of cardiac MR,and T2 prepulse steady state free procession during free breathing(T2 p-SSFP)sequence images of bright blood were collected.Pearson’s method was used to analyze the rela-tionship between T2WI sequences and myocardial injury as well as cardiac function indicators.Multivariate logistic regression analysis was used to evaluate the influencing factors of left ventricular diastolic dysfunction.Receiver operating characteristic(ROC)curve was used to analyze the diagnostic efficacy of cardiovascular MR T2WI sequences in left ventricular diastolic dysfunction.Results Com-pared with the T2-STIR sequence,the T2 p-SSFP sequence showed a significant decrease in the signal-to-noise ratio(SNR)of the dis-tal myocardial,the SNR of the edematous myocardial,and the contrast-to-noise ratio(CNR)of the edematous myocardial and the dis-tal myocardial(P<0.05).The distal myocardial SNR,edematous myocardial SNR,and edematous myocardial and distal myocardial CNR of T2WI sequences were positively correlated with cardiac troponin I(c Tn I),creatine kinase isoenzyme MB(CK-MB),myoglobin(MB),and left ventricular ejection fraction(LVEF),respectively(P<0.05).Compared with diastolic normal group,patients in diastolic dysfunction group had significantly higher distal myocardial SNR,edematous myocardial SNR,and edematous myocardial and distal myocardial CNR in the T2-STIR and T2 p-SSFP sequences(P<0.05).Logistic regression analysis showed that distal myocardial SNR,edematous myocardial SNR,and edematous myocardial and distal myocardial CNR were risk factors for left ventricular diastolic dysfunction in AMI patients(P<0.05).The ROC curve analysis showed that the distal myocardial SNR,edematous myocardial SNR,and edematous myocardial and distal myocardial CNR of T2WI sequences had diagnostic value for left ventricular diastolic dysfunction in AMI patients.Conclusion Cardiovascular MR T2WI sequences exhibit significant prominence in individuals diagnosed with AMI and demonstrate a positive correlation with myocardial injury.These sequences serve as valuable tools for assessing the disease’s severity and hold substantial predictive potential concerning left ventricular diastolic dysfunction.
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