Factors associated with early outcomes and discharge status in patients with severe traumatic brain injury undergoing decompressive craniectomy
Objective To investigate the independent predictors affecting early outcomes and discharge status of patients with severe traumatic brain injury(sTBI)who underwent decompressive craniectomy and to establish variable logistic regression equations.Methods Clinical data of 114 patients with severe brain injury admitted from January 2016 to January 2020 were collected and retrospectively analyzed through a hospital computerized electronic database,and subject working characteristic curves were plotted using univariate,multiple logistic regression and prognostic regression scoring equations to predict early outcomes and discharge status after brain trauma.Results We found that patients with sTBI treated with decompressive craniectomy who were≤50 years of age(P=0.034),had no past medical history(P=0.003),had bilateral pupil diameters<4 mm(P=0.001),had a GCS score>5 scores on admission(P=0.004),and did not have a tracheotomy(P=0.001)had better early outcomes and discharge status.The probability of predicting a favorable outcome using the subject working characteristic curve had an area under the curve of 79.0%,including a sensitivity of 66.7% and a specificity of 77.8% .Conclusion Our preliminary findings suggest that≤50 years of age,no past medical history,bilateral pupil diameters<4 mm,GCS crore>5 scores can be used as independent predictors to assess early prognosis and discharge status in patients with severe traumatic brain injury after undergoing decompressive craniectomy therapy.
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