Research progress of autophagy related signaling pathway and regulatory factors in breast cancer
Autophagy is a process in which cells degrade and reuse cytoplasmic proteins and organelles,and plays an important regulatory role in the occurrence and development of breast cancer.On one hand,autophagy can provide survival advantages,promote tumor cell growth and survival,and maintain cell homeostasis under stress and malnutrition.On the other hand,autophagy is also involved in the invasion,metastasis and drug resistance in breast cancer.Continuing to study the mechanism of autophagy and related signaling pathways is expected to providean important scientific basis for the treatment strategy and prognosis evaluation of breast cancer,and bring new breakthroughs and progress for the treatment and prognosis of breast cancer patients.This article reviews the role of autophagy related signaling pathway and regulatory factors in breast cancer.
breast cancerautophagysignaling pathwayprognosis evaluation
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维普
