Analysis of risk factors for permanent hypoparathyroidism after total thyroidectomy
Objective To investigate the risk factors for permanent hypoparathyroidism(HP)after total thyroidectomy and to assess the value of serum parathyroid hormone(PTH)levels measured on the first day after surgery in predicting permanent HP.Methods A total of 100 patients who underwent total thyroidectomy at The Second Affiliated Hospital of Shaoyang University from January 2022 to January 2024 were included.They were divided based on whether they developed permanent HP after surgery.Univariate and multivariate analyses were employed to identify risk factors associated with permanent HP.The predictive value of serum PTH levels measured on the first postoperative day was evaluated using a receiver operating characteristic(ROC)curve.Results The univariate analysis indicated that permanent HP was correlated with PTH and serum calcium levels on the first day after surgery,as well as factors such as central lymph node dissection,nano-carbon use,tumor maximum diameter,and thyroid maximum diameter(P＜0.05).The multivariate analysis identified serum PTH and serum calcium levels on the first day after surgery as independent risk factors for permanent HP after surgery.Additionally,the ROC curve showed that the serum PTH level on the first day after surgery was more effective in predicting permanent HP than the serum calcium level.Conclusion Low serum PTH and calcium levels on the first day after surgery significantly increase the likelihood of developing permanent HP.Moreover,the serum PTH levels measured on the first day after surgery have a superior predictive capability compared to serum calcium levels.
total thyroidectomypermanent hypoparathyroidism(HP)serum calcium
万方数据
维普
