Qualitative diagnosis of intrahepatic space-occupying lesions by multi-slice spiral CT and enhanced liver acquisition with volume acceleration
Objective The purpose of this study was to analyze the diagnostic performance of multi-slice spiral CT and enhanced liver acquisition with volume acceleration(LAVA)in the diagnosis of patients with intrahepatic space-occupying lesions(SOL).Methods 160 patients with intrahepatic SOL were encountered in our hospital between May 2020 and April 2023,and all underwent enhanced multi-slice spiral CT and LAVA scanning.The diagnostic efficacy of CT and LAVA scanning was analyzed based on the histo-pathological examination as the golden standard.Results Out of the 160 patients with intrahepatic SOL,the histo-pathological diagnosis included 87 malignant lesions(hepatocellular carcinoma in 79 cases and intrahepatic cholangiocarcinoma in 8 cases),and 73 benign lesions(cirrhotic nodules in 46 cases,nodular regenerative hyperplasia of liver in 20 cases and focal nodular hyperplasia in 7 cases;the CT diagnose malignant lesions in 77 cases and benign lesions in 83 cases,misdiagnosing 5 benign lesions into malignant and 15 malignant into benign ones,and the LAVA scan diagnose malignant in 86 cases and benign in 74 cases,misdiagnosing 3 benign lesions into malignant and 4 malignant into benign ones;the accuracy,sensitivity,specificity,positive predictive value and negative predictive value by CT scan were 87.5%,82.8%,93.2%,93.5%and 81.9%,while they were 95.6%,95.4%,95.9%,96.5%and 94.6%,respectively by LAVA scan,superior to those by CT diagnosis(P<0.05).Conclusion The qualitative diagnostic performance by MR LAVA is superior,which might help the clinicians make an appropriate decisions to intervene early.
HepatomaSpace-occupying lesionsCTEnhanced liver acquisition with volume accelerationDiagnosis