Optimal flip angle for image quality of biliary system under Gd-EOB-DTPA-enhanced MRI in patients with space-occupying lesions
Objective The study was conducted to investigate the optimal flip angle(FA)for image quality of the biliary system under disodium zocerate(Gd-EOB-DTPA)enhanced magnetic resonance imaging(MRI)in patients with space-occupying lesions(SOL).Methods Sixty patients with SOL were admitted to our hospital between July 2019 and July 2023,and all underwent Gd-EOB-DTPA-enhanced MRI by using a Philips Elition 3.0 scanner with five different sets of FA at 9°,20°,30°,45° and 60°.The bile duct,artifacts,signal-to-noise ratio and contrast-to-noise ratio of the biliary system with different FA were compared.Results At FA=45° and 60°,the estimated scores of cholangiography were(3.4±0.9)and(3.6±1.0),both significantly higher than at 9°,20° and 30°[(2.7±0.5),(2.9±0.8)and(3.2±0.8),respectively,P<0.05],suggesting with the increase of FA,the score of biliary duct imaging were getting greater and greater,that is,the image quality was getting better and better;as respect to the objective evaluation of biliary system,the differences of signal-to-noise ratio of gallbladder,common hepatic duct and common bile duct at each FA were statistically significant(P<0.05);at FA=30°,45° and 60°,the signal-to-noise ratios of gallbladder,left hepatic duct,right hepatic duct,common hepatic duct and common bile duct were significantly higher than those at FA=9°(P<0.05);the average signal-to-noise ratio of gallbladder,right hepatic duct and common hepatic duct were the best at FA=45°,while the average signal-to-noise ratio of left hepatic duct and common bile duct was the best at FA=30°;there were statistically significant differences in the signal-to-noise ratio of gallbladder,common hepatic duct and common bile duct at different FA(P<0.05);at FA=30°,45° and 60°,the signal-to-noise ratio of gallbladder,left hepatic duct,right hepatic duct,common hepatic duct and common bile duct were significantly higher than that at FA=9°(P<0.05);in addition,the average contrast signal-to-noise ratio of gallbladder,right hepatic duct,common hepatic duct and common bile duct were the best at FA=45°,while the average contrast signal-to-noise ratio of left hepatic duct was the best at FA=30°.Conclusions In 3T delayed imaging,the optimal FA of GdEOB-DTPA enhanced T1 weighted imaging of the liver and bile duct is 45 °,which could be used as a parameter setting basis for MR biliary imaging to improve the imaging quality.