实用肝脏病杂志2024,Vol.27Issue(5) :659-668.DOI:10.3969/j.issn.1672-5069.2024.05.005

双环醇防治肝脏炎性损伤多学科专家共识

Multidisciplinary expert consensus on prevention and treatment of inflammatory liver injury with bicyclol

中国医药生物技术协会慢病管理分会肝病学组 陆伦根 范建高
实用肝脏病杂志2024,Vol.27Issue(5) :659-668.DOI:10.3969/j.issn.1672-5069.2024.05.005

双环醇防治肝脏炎性损伤多学科专家共识

Multidisciplinary expert consensus on prevention and treatment of inflammatory liver injury with bicyclol

中国医药生物技术协会慢病管理分会肝病学组 陆伦根 1范建高2
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作者信息

  • 1. 上海,上海交通大学医学院附属第一人民医院消化内科 200080
  • 2. 上海,上海交通大学医学院附属新华医院消化内科 200092
  • 折叠

摘要

肝脏炎性损伤是许多慢性肝病的始动因素.肝脏炎性损伤可累及全身,反之,全身疾病也会导致肝损伤.肝病的诊治既要考虑肝脏病变本身,又需了解全身各系统疾病与肝脏炎性损伤之间相互影响及其病理生理发生机制.因此,针对肝损伤的诊治,常需多学科讨论,共同决策.肝病治疗的重要环节之一是保护和维持肝功能的稳定,其中如何进行抗炎护肝是制定治疗策略的重要考量因素之一.双环醇是由我国自主研发、用于治疗肝脏炎性损伤的一类化学药物,对各种原因所致的肝脏炎性损伤均具有较好的防治作用,已于"一带一路"沿线九国注册并上市.为此,我们组织了国内相关学科专家,根据肝病诊疗相关指南/共识/临床路径和循证医学证据,结合我国临床实践,总结双环醇在防治肝脏炎性损伤多学科临床应用方面的进展,旨在形成共识,提高双环醇临床使用的科学性和规范性,提升各学科对肝脏炎性损伤的防治水平.

Abstract

Objective Liver injury is common in many chronic liver disease,and liver disease has a systemic impact,and vice versa.Diagnosis and treatment of patients with liver disease should not only consider the liver disease itself,but also need to clarify patho-physiological mechanisms by which the interaction occur between various systemic diseases and inflammatory liver injury.Therefore,the dealing with liver injury often require multidisciplinary discussions and joint decision-making.One of the important aspects of liver disease treatment is to protect and maintain the stability of liver functions,and how to carry out anti-inflammatory and liver protection involves etiology and liver injuries for appropriate treatment strategies.Bicyclol is a chemical agent independently developed in China and has a widespread administration to treat patients with inflammatory liver injury.Bicyclol has a good preventive and therapeutic efficacy on inflammatory liver injury caused by various etiologies documented in literature,and has been registered and listed in nine countries along the Belt and Road.We have organized domestic experts from relevant disciplines all over the country to summarize multidisciplinary clinical application of bicyclol in the prevention and treatment of inflammatory liver injury abide on liver disease diagnosis and treatment guidelines/consensus/clinical pathways and evidence-based medicine,combined with clinical practice in China.The aim of this consensus is to improve the reasonable and standardized clinical application of bicyclol in the treatment of patients with inflammatory liver injury.

关键词

肝脏炎性损伤/双环醇/多学科/临床应用/药理作用/治疗

Key words

Inflammatory liver injury/Bicyclol/Multidisciplinary/Clinical application/Pharmacological effects/Thera-py

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出版年

2024
实用肝脏病杂志
中华医学会安徽分会

实用肝脏病杂志

CSTPCD
影响因子:1.362
ISSN:1672-5069
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