In order to verify the corrosion inhibition performance of phosphate ester under high temperature and aerobic condition,a polyethylene glycol phosphate ester was synthe-sized by using polyethylene glycol(PEG400),phenol,n-octanol and P2O5 as raw materials,and a quinoline phosphate compound corrosion inhibitor was formed by combining polyethy-lene glycol phosphate ester with benzyl chloride quaternary ammonium salts.The corrosion inhibition effect of quinoline phosphate compound corrosion inhibitor was studied by electro-chemical evaluation,and the protection effect of corrosion inhibitor under high temperature and aerobic condition was studied by high temperature autoclave evaluation.The results show that the average corrosion rate of N80 steel is 0.007 1 mm/a under the condition of 180℃,2 MPa CO2+0.02 MPa O2,there is no uniform corrosion and pitting trace after clean-ing,and the surface shows metallic luster.The compound corrosion inhibitor has good high temperature resistance and excellent corrosion inhibition performance.