Aiming at the problem that human machine interface has been paid less attention in the design by engineers, which lead to less reliability and usability of safety instrumented system, functions of main human machine interfaces in operation station, maintenance override switch, operational override switch, emergency shut-down button, reset button, alarm lamp and auxiliary consoles in safety instrumented system are analyzed.The existing problems in practical engineering are discussed in detail.The recommended solution is put forward.The practical installation, production and application indicate the solution has good effects.