Research on detection-dependent safety management of transgenic test bases in universities
[Significance]Transgenic technology,also known as genetic engineering or genetic modification(GM)technology,is an emerging field rooted in modern biotechnology.By transferring specific foreign genes into target organisms,this technology enables predictable and directed genetic changes.It has significantly contributed to the development of high-yield and high-quality crop varieties,playing a crucial role in ensuring global food security.Recognizing its potential,China has heavily focused on the research and development of agricultural GM technology.However,GM still poses certain environmental risks.For instance,transgenic plants can cross with related wild species through genetic drift,such as powder escape,leading to the unintentional release of genes into the natural environment.Therefore,GM should be strictly regulated at the present stage.The transgenic test bases of universities are important platforms for exploring genetic engineering technologies and their applications.Ensuring the safety of these bases is also paramount.However,effectively managing the cultivation of GM plants within these bases remains an open question for discussion.[Progress]Starting from the planting status of GM plants and their potential risks,this article mainly considers Zhejiang University as an example to introduce the management of the transgenic test base of the university.Particularly,it emphasizes the key role of transgenic detection in the safety management of transgenic test bases,detailing a comprehensive monitoring and traceability process.The process involves multitissue and multistage detection,involving the following stages:1)Before cultivation,GM-plant seeds are sampled and detected for their genetic backgrounds at protein and nucleic acid levels.2)During cultivation,leaves from GM seedlings and fruits or seeds from mature GM plants are sampled and detected.3)After harvesting,the soil residuary straws and roots of GM plants are sampled and detected.Overall,such thorough testing involving seeds,plants,and soil residuary roots aims to comprehensively regulate GM-plant cultivation,eliminating the risk of gene contamination and cross-contamination.[Conclusions and Prospects]Transgenic test bases in universities should excel not only in facilitating scientific research but also in rigorously controlling the cultivation of transgenic plants to prevent genetic contamination and associated potential risks.Therefore,developing a comprehensive review system and multilevel testing strategy is important.This article proposes a comprehensive regulatory strategy based on transgenic detection for the safety management of transgenic test bases in universities,offering new insights into transgenic safety management.
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