首页|卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血的效果及对凝血指标的影响

卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血的效果及对凝血指标的影响

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目的 探讨卡孕栓联合缩宫素在预防瘢痕子宫剖宫产产后出血中的应用效果及其对凝血指标的影响.方法 将94例行剖宫产手术的瘢痕子宫产妇随机分为观察组与对照组,每组47例.对照组在剖宫产产后采用缩宫素进行止血,观察组采用卡孕栓联合缩宫素进行止血.比较2组临床效果、产后出血量、凝血指标以及不良反应.结果 与对照组相比,观察组总有效率显著升高,产后2、24 h出血量显著减少,活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)显著缩短,D-二聚体(D-D)、纤维蛋白原(FIB)水平显著升高,差异均有统计学意义(P<0.05);2组不良反应发生率比较,差异无统计学意义(P>0.05).结论 卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血效果显著,利于减少产妇产后出血量,改善产妇凝血功能,且安全性较高.
Preventing Postpartum Hemorrhage after Caesarean Section with Scarred Uterus by Kagai Suppository Combined with Oxytocin and Its Effect on Coagulation Index
Objective To investigate the effect of Kagai suppository combined with oxytocin on the prevention of postpartum hemorrhage after caesarean sectionwith scarred uterus and its effect on coagulation index.Methods A total of 94 women with scar uterus who underwent cesarean section were randomly divided intoobservation group andcontrol group,with 47 cases in each group.In the control group,hemostasis was carried out by using oxytocin after cesarean section delivery;in the observation group,it was carried out by using Kagai suppository combined with oxytocin.The clinical effect,postpartum hemorrhage,coagulation index,and adverse reaction were compared between the two groups.Results Compared with the control group,the total effective rate of the observation group was higher;blood loss was significantly reduced at 2 and 24 h post-partum;the activated partial thromboplastin time(APTT)and prothrombin time(PT)were sig-nificantly shorter;the levels of D-dimer(D-D)and fibrinogen(FIB)were significantly higher;there was nostatistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Kagai suppository combined with oxytocinmay be effective in preventing postpartum hemorrhage in cesarean section with scarred uterus,which may be condu-cive to reducing postpartum hemorrhage and improving maternal coagulation function,and may have a high degree of safety.

scarred uteruscaesarean sectionpostpartum hemorrhagecard pregnancy suppositoryoxytocincoagulation index

梁静、谢佩真

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莆田市妇幼保健院妇女保健科

菁田学院附属医院妇产科,福建莆田 351100

瘢痕子宫 剖宫产 产后出血 卡孕栓 缩宫素 凝血指标

2024

实用临床医学
南昌大学

实用临床医学

影响因子:0.818
ISSN:1009-8194
年,卷(期):2024.25(1)
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