Distribution Analysis of Pathogens of Lower Respiratory Tract Infections in Children in Ganzhou
Objective To investigate the pathogenetic and epidemiologic characteristics of low-er respiratory tract infections in children aged 0-14 years in Ganzhou.Methods 382 children with lower respiratory tract infections admitted to the Department of Pediatrics of our hospital from October 2021 to October 2023 were retrospectively analyzed;indirect fluorescence immunoassay was used to detect respiratory syncytial virus(RSV),adenovirus(HAdV),influenza virus type A(FluA),influenza virus type B(FluB),parainfluenza virus(HPIV),mycoplasma pneumoniae(MP),chlamydia pneumoniae(CP),legionella pneumophila(LP),Coxsackievirus A(CoxA),Cox-sackievirus B(CoxB),and Echovirus(ECHO)IgM antibodies;the results of the tests were sum-marized and analyzed.Results Among the 383 children with lower respiratory tract infections,231 cases(60.3％)were reported positive,in which the main infectious agent was mycoplasma pneumoniae;the difference in the positivity rate of the detection of the various pathogens was not statistically significant when comparing male children and female children(P＞0.05);the positive detection rate of MP ranked first in all seasons,but the difference was not statistically significant(P＞0.05);the positive detection rate of FluA was significantly higher in winter than in other seasons(P＜0.05);the positive detection rate of LP and FluB was significantly higher in summer and winter than in spring and fall(P＜0.05).There was a significant difference in the total posi-tive detection rate of respiratory pathogens in different age groups(P＜0.05),with the positive detection rate of FluB in the preschool and school-age groups being significantly higher than that of the infant and toddler groups(P＜0.05),and the positive detection rate of LP in the preschool group being significantly higher than that of the infant and toddler group(P＜0.05).Conclusion The findings suggest that children with lower respiratory tract infections in Ganzhouhave high rates of infection with atypical pathogens MP,LP,and CP,mainly MP infections,which are sus-ceptible throughout the year,while influenza viruses have obvious seasonal and age differences,with preschool and school-age children having higher susceptibility to influenza viruses than in-fants and young children,and winter being the high season.
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