The Application of a Vibrating Mesh Nebulizer Connected to An Invasive Ventilator Circuit in Patients with Structural Lung Disease Complicated by Respiratory Failure
Objective To explore clinical efficacy of a vibrating mesh nebulizer connected to an invasive ventilator circuit in patients with structural lung disease and respiratory failure.Methods 40 patients with structural lung disease who also exhibited respiratory failure admitted from August 2022 to August 2023 were selected and divided into the control group(n=20)and the observation group(n=20)according to the method of randomized numerical table;the patients in both groups were given invasive ventilator-assisted respiration,with air-compressing nebulizer in the control group and vibrating mesh nebulizer in the observation group;ventilator-related indexes,nebulizer-related indexes and recovery conditions were monitored in the 2 groups.Results During nebulization,there were no statistically significant differences in respiratory rate between the 2 groups(P＞0.05);however,the peak inspiratory pressure(PIP)and tidal volume(VT)levels in the observation group were significantly lower than those in the control group(P＜0.05).Additionally,nebulization time,operational time for nebulization,remaining volume of nebulized medication,and the number of tidal volume alarms from the ventilator were all significantly reduced in the observation group compared to the control group(P＜0.05).The levels of partial pressure of oxygen(PaO2)were higher and the levels of partial pressure of carbon dioxide(PaCO2)were lower in both groups after nebulization treatment than before(P＜0.05);1 week after treatment,the observation group showed higher PaO2 and lower PaCO2 levels than the control group(P＜0.05).Conclusion Vibrating mesh nebulizers and air-compressing nebulizers can improve the indexes of blood gas analysis in the management of patients with structural lung disease complicated by respiratory failure,and the findings suggest that vibrating mesh nebulizers exert less impact on tidal volume,have higher drug utilization,and need less operation time.
万方数据
维普
