The Application Effect of Improved Replacement Fluid Formula in Daytime Intermittent CRRT for Patients with Severe Maintenance Hemodialysis
Objective To explore the application effect of improved replacement fluid formula in daytime intermittent continuous renal replacement therapy(CRRT)for patients with severe maintenance hemodialysis.Methods 30 patients with severe maintenance hemodialysis admitted to the First Affiliated Hospital of Nanchang University from July 2022 to July 2023 were selected as the study subjects.All patients underwent daytime intermittent CRRT and were divided into a control group and an observation group using a random number table method,with 15 patients in each group.The control group received the original standard replacement fluid formula,while the observation group received an improved replacement fluid formula.After 3 months of treatment,renal function,blood glucose,potassium,sodium,chloride,calcium,blood gas levels,and the incidence of adverse events were compared between the 2 groups.Results The levels of blood urea nitrogen(BUN)and serum creatinine(Scr)in the observation group were significantly lower than those in the control group after starting the machine(P＜0.05),while the levels of potassium,sodium,chloride,and calcium were significantly higher than those in the control group(P＜0.05);The pH value and HCO3-level in the observation group were significantly higher than those in the control group at 6 hours after starting the machine and after stopping the machine(P＜0.05).There were no statistically significant differences in the incidence of hypoglycemia,infection,disequilibrium syndrome,hypotension,and fistula lesions between the 2 groups during the intervention process(P＞0.05).Conclusion Improved replacement fluid formula can enhance renal functions in daytime intermittent CRRT for patients with severe persistent hemodialysis,contributing to improving the levels of blood glucose,potassium,sodium,chlorine,calcium,and blood gas,without increasing the incidence of adverse events.
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维普
