Diagnostic Value of Ophthalmic Artery Ultrasonic Blood Flow Parameters in T2DM with Retinopathy and Its Assessment of the Degree of Lesion
Objective To investigate the diagnostic value of ophthalmic artery ultrasonic blood flow parameters in type 2 diabetes mellitus(T2DM)complicated with retinopathy and its assessment of the severity of the lesion.Methods A retrospective study was conducted;80 patients with T2DM complicated with retinopathy admitted to the hospital from March 2023 to March 2024 were selected as the study subjects(the lesion group),and another group of patients with simple T2DM who received treatment during the same period was established as the non-lesion group.The ophthalmic artery ultrasonic blood flow parameters[peak systolic velocity(PSV),end diastolic velocity(EDV),resistance index(RI)of central retinal artery(CRA),and PSV,EDV and RI of ophthalmic artery(OA)]were measured and compared between the 2 groups;the diagnostic value of ophthalmic artery ultrasonic blood flow parameters in the occurrence of retinopathy in T2DM patients was analyzed using receiver operating characteristic(ROC)curves.Based on the severity of retinopathy in T2DM patients,patients with proliferative retinopathy were included in the proliferative group(37/80),and patients with non-proliferative retinopathy were included in the non-proliferative group(43/80);ROC was used to analyze the value of ophthalmic artery ultrasonic blood flow parameters in determining the severity of retinopathy in T2DM patients.Results The CRA-PSV,CRA-EDV,OA-PSV and OA-EDV in the lesion group were lower than those in the non-lesion group(P＜0.05),whereas the CRA-RI and OA-RI were higher than those in the non-lesion group(P＜0.05);the results of ROC curve showed that CRA-PSV,CRA-EDV,CRA-RI,OA-PSV,OA-EDV,OA-RI,and their combined detection had AUC values greater than 0.70 for diagnosing T2DM patients with retinopathy,indicating their diagnostic value.Among them,the combined detection had the highest diagnostic efficiency.CRA-PSV,CRA-EDV,OA-PSV and OA-EDV in the proliferative group were lower than those in the non-proliferative group(P＜0.05),whereas CRA-RI and OA-RI were higher than those in the non-proliferative group(P＜0.05);the results of ROC curve demonstrated that CRA-PSV,CRA-EDV,CRA-RI,OA-PSV,OA-EDV,OA-RI,and their combined detection had AUC values greater than 0.70 for assessing the severity of retinopathy in T2DM patients,indicating their evaluative value.Among them,the combined detection exhibited the highest evaluative efficiency.Conclusion The findings suggest that ophthalmic artery ultrasonic blood flow parameters have potential value in the diagnosis of T2DM complicated with retinopathy and can effectively assess the severity of retinopathy in these patients.
type 2 diabetes mellitusretinopathyophthalmic arteryultrasonic blood flow parameterthe degree of lesion
NETL
NSTL
万方数据
