The Effects of Warmed and Humidified CO2 Pneumoperitoneum on Patients with Laparoscopic Hepatectomy
Objective To investigate the effects of warmed and humidified CO2 pneum-operitoneum on body temperature and blood lymphocyte to C-reactive protein ratio(LCR)in patients undergoing laparoscopic hepatectomy.Methods The data for 96 patients who underwent laparoscopic hepatectomy were collected and they were randomly divided into 2 groups based on CO2 temperature and humidity during artificial pneumoperitoneum:a conventional pneumoperitoneum group(conventional group,n=46)and a warmed and humidified pneumoperitoneum group(intervention group,n=50).In the conventional group,pneumoperitoneum was established using normal temperature CO2(cold CO2 with 20%relative humidity),whereas in the intervention group,pneumoperitoneum was created using CO2 that had been warmed to 37℃ and maintained at 98%humidity.Perioperative bladder temperature was monitored,routine blood tests were conducted,and serum LCR levels were measured using ELISA.Changes in deep body temperature and LCR were compared between the 2 groups at preoperative time point(T0),10 minutes(T1),60 minutes(T2),and 90 minutes(T3)after pneumoperitoneum,as well as 60 minutes(T4)and 24 hours(T5)postoperatively.Results In terms of deep body temperature,there was no statistically significant difference between the 2 groups at T0 and T1(P＞0.05);however,at T2,T3,and T4,the intervention group had higher deep body temperatures than the conventional group(P＜0.05).In terms of LCR,there was no statistically significant difference between the 2 groups at T0(P＞0.05),and at T1,T2,T3,and T5,the intervention group showed a slower decrease in LCR compared to the conventional group(P＜0.05).Conclusion Warmed and humidified CO2 pneumoperitoneum can positively reduce the occurrence of intraoperative and postoperative hypothermia in patients with laparoscopic hepatectomy,contributing to the protection of immune function and the mitigation of hypothermia-related complications among patients.
hepatectomypneumoperitoneum37℃ CO298%humidity CO2deep body temperatureblood lymphocyte to C-reactive protein ratio
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