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环境暴露与肌少症的关系研究进展

Relationship between environmental exposure and sarcopenia

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随着社会飞速发展,环境污染的危害日益凸显.人口老龄化加剧的背景下,肌少症病人的数量不断增加,加剧了国家公共卫生负担.本文综述了常见环境暴露如空气污染、重金属暴露、噪音污染等对肌少症的影响及机制,阐明环境污染导致机体的线粒体功能障碍和慢性炎症等一系列分子生物学机制与肌少症的发生进展有着密不可分的联系,强调重金属暴露的危害,旨在为肌少症的临床诊治和科学研究提供新思路.
With the rapid development of society,the harm of environmental pollution has become increasingly prominent.With the progress of population aging,the prevelence of sarcopenia is increasing,which increases the national public health burden.This article reviews the effects and mechanisms of common environmental exposures such as air pollution,heavy metal exposure and noise pollution on sarcopenia,and elucidates that mitochondrial dysfunction and chronic inflammation caused by environmental pollution are closely related to the occurrence and progression of sarcopenia,and emphasizes the hazards of heavy metal exposure,in order to provide new ideas for the clinical diagnosis,treatment,and scientific research of sarcopenia.

environmental exposuresarcopeniaheavy metal exposureair pollution

董小菲、张飞、王佳贺

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110000 辽宁省沈阳市,中国医科大学附属盛京医院全科医学科

环境暴露 肌少症 重金属暴露 空气污染

2025

实用老年医学
江苏省老年医学研究所

实用老年医学

影响因子:0.724
ISSN:1003-9198
年,卷(期):2025.39(1)