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聚丙烯酰胺水凝胶隆乳术后特殊并发症临床分析

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目的 探讨聚丙烯酰胺水凝胶(polyacrylamide hydrogel,PAAG)隆乳术后并发结节的病因及与乳腺癌的潜在关系.方法 回顾性分析自 2015 年 8 月至 2023 年 5 月,联勤保障部队第九八〇医院烧伤整形科收治 45 例PAAG注射隆乳术后并发结节患者,联合术前影像、术中探查结节情况、病理结果及术后随访,综合分析结节类型及其诱发因素.结果 45 例患者中,单纯乳腺来源结节 12 例,异物结节 25 例,混合存在者 8 例;送检结节共 113 个,术后病理回报乳腺增生伴局灶导管扩张 25 个(22.1%),纤维组织增生伴黏液变性、钙化 13 个(13.3%);异物结节伴多核巨细胞反应 75 个(64.6%),术后随访 1~6 个月均未提示癌变,但术后乳房均有含量不等的异物残留.结论 异物结节及组织变性是PAAG注射隆乳术后常见并发症,需要与乳腺癌相鉴别,应尽早行注射物取出术,对于注射物残留者建议长期随访.
Clinical analysis of special complications after polyacrylamide hydrogel injection for breast augmentation
Objective To investigate the etiology of nodules after polyacrylamide hydrogel injection for breast augmentation and its potential relationship with breast cancer.Methods From August 2015 to May 2023,45 patients with breast nodules after polyacry-lamide hydrogel injection in our department were reviewed.Preoperative imaging,intraoperative exploration of nodules,pathological analy-sis and postoperative follow-up were combined to comprehensively analyze the types of nodules and the inducing factors.Results Among the 45 patients,there were 12 simple breast nodules,25 foreign body nodules and 8 mixed ones,113 nodules were send for pathological examination,22.1%result to be mammary hyperplasia with focal duct dilatation,13.3%result to be fibrous hyperplasia with mucous de-generation and calcification.Foreign body nodules accompanied by ultinuclear giant cell reaction accounted for 64.6%.Complete removal was impossible,but followed up for 1 to 6 months,there were no signs of cancer.Conclusion Foreign body nodules and tissue denatura-tion are common complications after polyacrylamide hydrogel injection for breast augmentation,which should be distinguished from breast cancer.Early surgical removal for the patients received injections and long-term follow-up for the patients with residual injectant is recom-mended.

Polyacrylamide hydrogelBreast augmentationComplicationForeign body nodules

姚媛媛、张程亮、安亮恩、吴泽义、随振阳、滕志鹏、仇树林、李晓东

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联勤保障部队第九八〇医院(原解放军白求恩国际和平医院)烧伤整形科,河北 石家庄 050082

聚丙烯酰胺水凝胶 注射隆乳术 并发症 异物结节

2024

中国美容整形外科杂志
中国医师协会 辽宁省人民医院 沈阳军区总医院

中国美容整形外科杂志

CSTPCD
影响因子:0.605
ISSN:1673-7040
年,卷(期):2024.35(2)
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