促胶原再生材料的临床应用进展
Progress in clinical application of collagen-promoting materials
张榕 1孙怡馨 1俞楠泽 1丁文蕴 1龙笑1
作者信息
- 1. 中国医学科学院北京协和医学院北京协和医院整形外科,北京 100730
- 折叠
摘要
胶原再生是一个复杂的生物过程,涉及到多种细胞类型和多种生长因子.促胶原再生材料通常由生物材料或合成物质制成,可以刺激皮肤细胞的增殖和分化.目前市场上存在多种促胶原再生材料,但不同材料的效果和安全性存在差异.现就钙经基磷灰石(calcium hydroxylapatite,CaHA)、聚左旋乳酸(poly-L-lactic acid,PLLA)、聚己内酯(poly-caprolactone,PCL)3 种促胶原再生材料的作用机制、应用及不良反应作一综述.
Abstract
Collagen regeneration is a complex biological process that involves a variety of cell types and growth factors.Pro-colla-gen regeneration materials are usually made of biological materials or synthetic substances,which can stimulate the proliferation and differ-entiation of skin cells.At present,there are many kinds of pro-collagen regeneration materials on the market,but the effects and safety of different materials are different.In this paper,the mechanism of action,application and adverse reactions of Calcium hydroxylapatite(Ca-HA),poly-L-lactic acid(PLLA)and poly-caprolactone(PCL),which promote collagen regeneration,are reviewed.
关键词
胶原再生/材料/注射技术/真皮填充剂/CaHA/PLLA/PCLKey words
Collagen regeneration/Materials/Dermal filler/Injection techniques/CaHA/PLLA/PCL引用本文复制引用
出版年
2024
NETL
NSTL
万方数据