Progress in clinical application of collagen-promoting materials
Collagen regeneration is a complex biological process that involves a variety of cell types and growth factors.Pro-colla-gen regeneration materials are usually made of biological materials or synthetic substances,which can stimulate the proliferation and differ-entiation of skin cells.At present,there are many kinds of pro-collagen regeneration materials on the market,but the effects and safety of different materials are different.In this paper,the mechanism of action,application and adverse reactions of Calcium hydroxylapatite(Ca-HA),poly-L-lactic acid(PLLA)and poly-caprolactone(PCL),which promote collagen regeneration,are reviewed.
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