Objective Comparing two detection methods for chlamydial trachomatis in the genital tract(GeneXpert® CT/NG and Roche® Cobas 4800 CT/NG),we summarize their respective advantages and disadvantages to provide references for the promotion and application of these two methods.Methods During a field survey conducted in a sample hospital,a convenience sampling method was employed to select 60 patients.Vaginal swabs were collected from these patients for testing using the GeneXpert® CT/NG system,while urine samples were collected for testing with the Roche® Cobas 4800 CT/NG system.Staff members were tasked with recording and compiling data related to the testing process,including the time taken for testing,the cost of testing,and the positive detection rates.This data was then used to compare the two testing methods.Results The testing time for Roche® Cobas 4800 CT/NG is 293 minutes,while the testing time for GeneXpert® CT/NG is 92.95 minutes.In other words,the testing time for Roche® Cobas 4800 CT/NG is 3.15 times longer than that of GeneXpert® CT/NG;When the number of tests conducted in the sample hospital reaches 3000 cases,the cost of Roche® Cobas 4800 CT/NG testing is approximately 1/5 of that of GeneXpert® CT/NG testing.As the number of tests increases,when the volume reaches 200,000 cases,the unit cost of Roche® Cobas 4800 CT/NG testing is approximately 1/3 of the unit cost of GeneXpert® CT/NG testing;Among the 60 participants in this study,11 cases of CT positive patients were detected by GeneXpert® CT/NG,with a CT positive rate of 0.183.Roche®Cobas 4800 CT/NG detected 10 cases,with a CT positive rate of 0.167.Conclusion The GeneXpert® CT/NG test has a significant time advantage,as it takes less time and provides faster results;The Roche® Cobas 4800 CT/NG test has a cost advantage,with lower detection costs;The GeneXpert® CT/NG test has a higher positive detection rate.
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