Objective To verify the experimental method of erythromycin ointment.Methods Three batch numbers of erythromycin ointment(S1～S3)were selected and divided into three washing methods:test group and positive and negative control group(test article control group and bacterial solution control group).The microbial limit detection method of erythromycin ointment was analyzed by test.Results The recovery ratio of oxygen bacteria,yeast,mold and added bacteria required for different batches of erythromycin ointment in the test is between 0.5 and 2,and the inhibition of microbial strains of erythromycin ointment test can be adopted by membrane filtration method.Therefore,all the methods can effectively eliminate the antibacterial components of erythromycin ointment,and the experimental results can truly reflect the microbial contamination of erythromycin dye ointment.Conclusion The application of centrifugal method in antibacterial removal will not affect the microbial limit test of erythromycin ointment.
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