Objective To explore the pathogenic factors causing outbreaks of bacterial foodborne diseases.Methods Collecting anal swabs,food retention samples,and food processing tool application samples from patients affected by this epidemic,refer to"Microbiological Testing of Food Hygiene"(GB/T 4789.4-2016、GB/T 4789.5-2012、GB/T 4789.6-2016,GB/T 4789.7-2013,GB/T 4789.10-2016)and"National Clinical Testing Operating Procedures"(Fourth Edition).Results Aeromonas sobria was detected in food samples from little yellow croaker and anal swabs from two patients.Aeromonas hydrophila was detected in a kitchen appliance application and one patient's anal swab.Conclusion This was a rare outbreak of foodborne disease caused by mixed Aeromonas,In the diagnosis and treatment of intestinal infectious diarrhea,in addition to considering common intestinal pathogenic bacteria,rare pathogenic bacteria such as Aeromonas should not be ignored to avoid clinical diagnosis and treatment difficulties.