Improvement and Extended Design of Classical Organic Chemistry Teaching Experiments
The preparation of coumarin-3-carboxylic acid is one of the classic organic experiments for college students.In this experiment,coumarin-3-carboxylic acid ethyl ester is prepared via Knoevenagel reaction catalyzed by piperidine.However,piperidine is controlled and corrosive.Furthermore,this experiment only includes the preparation and purification of organic products.Therefore,the following improvements and extensive designs are made.Ionic liquid is adopted to catalyze this reaction.The fluorescence on-off experiment of coumarin-3-carboxylic acid complex is designed.This experiment involves the knowledge of multiple disciplines of organic synthesis,green chemistry and coordination chemistry.It has strong comprehensiveness,interest and teaching feasibility,and is conducive to the cultivation of students'green chemistry concept and comprehensive application ability.
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