Predictive Value of Fibronectin for Major Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction within One Year after Percutaneous Coronary Intervention
Objective To explore the predictive value of fibronectin(FN)for major adverse cardiovascular events(MACE)in patients with acute myocardial infarction within one year after percutaneous coronary intervention.Methods A total of 346 acute myocardial infarction patients who underwent percutaneous coronary intervention in the Department of Cardiology,Zhongda Hospital Southeast University from September 2021 to December 2022 were selected as the research objects.According to the occurrence of MACE within one year after percutaneous coronary intervention,the patients were divided into the MACE group(n=56)and the non-MACE group(n=290).Clinical data of patients were collected.Multivariate Logistic regression analysis was used to analyze the influencing factors of MACE in acute myocardial infarction patients within one year after percutaneous coronary intervention.ROC curve was drawn to evaluate the predictive value of FN for MACE in acute myocardial infarction patients within one year after percutaneous coronary intervention.Results There were significant differences in age,smoking rate,incidence of hypertension,incidence of diabetes,Killip grade,LVEF,FN,HDL-C,TC between the two groups(P<0.05).Multivariate Logistic regression analysis showed that,age[OR=1.066,95%CI(1.015-1.119)],Killip grade[OR=1.969,95%CI(1.296-2.992)],LVEF[OR=0.946,95%CI(0.908-0.986)]and FN[OR=1.031,95%CI(1.013-1.050)]were independent influencing factors of MACE in acute myocardial infarction patients within one year after percutaneous coronary intervention(P<0.05).ROC curve analysis showed that,the AUC of FN in predicting MACE in acute myocardial infarction patients within one year after percutaneous coronary intervention was 0.825[95%CI(0.768-0.881)].Conclusion FN is an independent influencing factor of MACE in acute myocardial infarction patients within one year after percutaneous coronary intervention,and it has certain predictive value for MACE in acute myocardial infarction patients within one year after percutaneous coronary intervention.
万方数据
维普
