Research progress about skin lipids and transdermal drug delivery of liposomes resembling skin lipids
Objective To review skin lipids and liposomes resembling skin lipids(LRSL).Methods Referring to 209 literatures at home and abroad,the composition and content of skin lipids,functions of skin lipids and skin diseases were summarized,and the discovery,formation and stability,lipid composition,morphology and size,preparation methods,changes in vivo,advantages and applications of LRSL were summarized and analyzed.Results LRSL could deliver the effective components to the deep layer of skin with good stability and safety,and could play a role in repairing skin barrier.Therefore,LRSL had great advantages and feasibility in drug therapy.Conclusion The present work provides reference for the development of LRSL.
skin lipidsliposomes resembling skin lipidstransdermal drug delivery
万方数据
维普
