Optimization of extraction process of β-ecdysterone from Xitongkang based on Box-Behnken response surface methodology
Objective To optimize the extraction process of β-ecdysterone in Xitongkang formula.Methods The soaking time,extraction times,extraction time and methanol multiplicity in the extraction process were optimized by using one-way test and Box-Behnken response surface method,and the optimal extraction process conditions were obtained through response surface model analysis and prediction,and the optimal conditions were verified.Results The optimal extraction process of Cynodon grandiflorus was as follows:the slices was soak for 96 min and extracted for 2 times,100 min for each 16 times of methanol were used.Conclusion The extraction method was characterized by simple equipment,low cost and stable extraction process.Moreover,the extraction process has good application value which could provide theoretical basis for the application of Xitongkang.
Achyranthis bidentatae Radixβ-ecdysteroneBox-Behnken response surface methodextraction process
万方数据
维普
