Research progress in clinical application of clofazimine
Objective Clofazimine(CFZ)is an imiphenazine,which has a wide range of antibacterial activities from leprosy to non-tuberculous mycobacterial diseases.CFZ has become a research hotspot due to its good pharmacokinetic characteristics,dose-dependent side effects and low price.Modern clinical studies have found that it also has good efficacy in skin diseases,stomatitis,parasites,viruses and tumors.The article reviews the recent progress and adverse reactions of CFZ in clinical application,summarizes the current status of CFZ in treatment and the possible direction of future clinical application,so as to provide reference for clinical medication.