At present,surgery combined with chemotherapy is still the main treatment for primary hepatocellular carcinoma(primary hepatic carcinoma,PHC),but most chemotherapy drugs will cause serious side effects,and the long-term benefits of patients are still not ideal.As a new discipline,nanotechnology can synthesize nano-drugs loaded particles,and the synthetic nano drugs are widely used in the treatment of PHC because of their advantages,such as stable physical and chemical properties,good biocompatibility and low toxicity.It can play a variety of new functions through hyperthermia,targeted chemotherapy,radiotherapy and other treatment methods to improve the treatment effect and prognosis of patients.However,the integrity and stability of nano drugs are greatly affected by the carrier materials,which may affect the therapeutic effect to some extent.In the future,nano drug loading technology needs to be further improved,so that nano drugs can play a better role in the treatment of PHC.
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