Research progress of nanocrystals based on different action mechanisms and their applications
Objective Because of their nanoscale size and high solubility,nanocrystals(NC)have gradually become a research focus in pharmaceutical field to improve the absorption and bioavailability of insoluble drugs.This article focuses on the absorption mechanism of NC in injection,ocular,transdermal and pulmonary drug delivery routes,the action advantages and the latest research progress in disease treatment,in order to provide reference for the further development of NC.
nanocrystalsroute of administrationabsorption mechanismaction advantagestherapeutic ap-plication