局限期小细胞肺癌的放射治疗进展
Radiotherapy advances in limited-stage small cell lung cancer
曲皎月 1汪庚明1
作者信息
- 1. 蚌埠医学院第一附属医院放疗科,安徽 蚌埠 233000
- 折叠
摘要
当前,同步放化疗及预防性颅脑照射是局限期小细胞肺癌的标准治疗方案.尽管其疗效明显,但仍有1/3的患者会出现局部复发.为探讨如何最大程度控制局部复发及提高生存期,本文分析了局限期小细胞肺癌放射治疗的研究现状,探索其最佳放射时机、靶区、剂量、分割方式,及预防性颅脑照射.此外,还对局限期小细胞肺癌新兴的放射治疗联合免疫治疗进行了概述.
Abstract
At present,concurrent chemoradiotherapy and prophylactic craniocerebral irradiation are the standard treatment for limited-stage small cell lung cancer.Despite its obvious efficacy,1/3 of patients still have local recurrence.In order to explore how to maximize control of local recurrence and improve survival,this article reviews the current status of radiotherapy for limited-stage small cell lung cancer,and explores its optimal timing,target area,dose,segmentation,and prophylactic craniocerebral irradiation.In addition,emerging therapies of radiotherapy combined with immunotherapy in limited-stage small cell lung cancer are also reviewed.
关键词
小细胞肺癌/局限期/放射治疗/免疫治疗Key words
small cell lung cancer/limited-stage/radiotherapy/immunotherapy引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据