Objective:To retrospectively analyze the distribution and changes in common pathogenic bacteria isolated from inpatients in department of neurosurgery and their resistance,so as to provide a basis for the rational use of antimicrobial drugs and the control of pathogen resistance rates.Methods:The results of 7 636 specimens from neurosurgery inpatients admitted to the hospital between Jul 1,2020,and Jul 1,2023 were collected and analyzed.The distribution and resistance rates of infecting pathogens were analyzed as well.Results:Out of 7 636 specimens,3 205 strains of pathogenic bacteria were isolated.Sputum specimens were the most common,totaling 2 790 strains,accounting for 87.05%of all.Gram-negative bacteria were the predominant isolates,with 2 586 strains,accounting for 80.69%.The resistance rates of both Gram-negative and Gram-positive bacteria showed an increasing trend,while the resistance rate of fungi showed a decreasing trend.Gram-positive bacteria remained highly sensitive to vancomycin and linezolid.Conclusion:Among the cultured specimens obtained from inpatients in neurosurgery,Gram-negative bacteria are the predominant isolates,and there is an overall increasing trend in the resistance rates of the pathogens over the years.
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